BINDER Incubator BD 400

BINDER BD 400 Incubator

The BINDER BD 400 incubator provides laboratory professionals and research institutions with a device that has been specially developed for demanding breeding and incubation applications. Thanks to its generous internal volume of 400 litres and precise temperature control, this powerful incubator is ideal for processes in the fields of microbiology, biotechnology, and pharmaceutical quality control. The innovative apt.line preheating chamber technology ensures extremely even and rapid temperature distribution, enabling precise cultivation results and high process reliability. Compared to similar products, this incubator stands out thanks to its excellent temperature stability, reliable energy efficiency, and robust, laboratory-suitable design.

Features and technical specifications at a glance

The BD 400 is positioned as a versatile incubation solution for medium to large-volume sample series, such as those routinely encountered in microbiological, biotechnological and pharmaceutical laboratories. Key technical highlights and features include:

• Internal volume: 400 litres, ideal for extensive sample series and large batches
• Temperature range: Precise control from 5 °C above room temperature up to 100 °C
• Temperature precision: Spatial deviation only ±0.5 K at 37 °C (±0.9 K at 50 °C), temporal deviation ±0.1 K
• Heating times: 105 minutes to 37 °C, 132 minutes to 50 °C
• Maximum load: 100 kg, load capacity per grid: 35 kg, up to 10 insert grids possible
• Dimensions: External: W 1235 x H 1025 x D 765 mm; Internal: W 1000 x H 800 x D 500 mm
• Energy efficiency: Only 56 W consumption in continuous operation at 37 °C, rated power 0.85 kW

Operation is via a user-friendly, intuitive control panel. The BD 400 has two doors for easy loading and flexible interior configuration. The device is protected against unwanted ingress of solid objects in accordance with IP20 (EN 60529). Process reliability is ensured by compliance with the standards and manufacturing standards declared by the manufacturer, in particular compliance with DIN 12880 for temperature accuracy and stability.

Binder's apt.line preheating chamber technology is a special feature that ensures excellent reproducibility and homogeneity of temperature distribution in the interior. This reliably eliminates sources of error in parallel experiments and long-term incubations.

Also worth mentioning is the option of placing up to 10 grids, allowing flexible use for a wide variety of sample vessels - from Petri dishes and bottles to special plate formats.

Certifications and standards

• DIN 12880: Compliance with the standard for temperature precision and temperature stability in incubators
• EN 60529 (IP20): Protection against solid foreign objects up to 12.5 mm in diameter
• Quality-controlled factory standards for measuring and documenting temperature distribution

These standards make the device particularly attractive for use in GMP-regulated laboratories and accredited testing and control institutes.

Specific application examples

The BD 400 is versatile and covers a wide range of typical laboratory processes:

• Cultivation and propagation of microorganisms: Optimal conditions for bacterial species such as Escherichia coli or Staphylococcus aureus as well as for yeasts and moulds.
• Stability testing in pharmaceuticals: Used for the ageing and stability-oriented storage of pharmaceutical preparations under strictly controlled temperatures.
• Cell culture incubation: Suitable for adherent and suspension-cultured cell lines; commonly used in the manufacture of vaccines or biological agents.
• Quality control and shelf life testing: Storage and incubation of food, cosmetics and diagnostics under reproducible conditions.
• Testing of active substances and sample storage: Short-term or long-term temperature control of sensitive samples, e.g. reference substances, solutions or test kits.

Typical substances processed in this incubator include tryptic soy agar (TSA), Luria-Bertani broth (LB), nutrient broth, cell culture media (DMEM, RPMI) and pharmaceutical stability standards according to ICH.

FAQs

How quickly is the temperature restored after opening the door?

The recovery time is 6 minutes to 3 °C and 29 minutes to 5 °C, measured after 30 seconds with the door open. This guarantees minimal interruptions for sensitive processes.

Can multiple samples be incubated simultaneously without temperature deviation?

Thanks to the apt.line preheating chamber and the low spatial and temporal temperature extremes, the uniform incubation of up to 10 sample series is reliably guaranteed.

Is the device suitable for use in clean rooms?

The BD 400 complies with IP20 and meets laboratory quality standards, making it suitable for standard and special laboratories. However, specific clean room requirements should be agreed with the manufacturer.

How can energy consumption be assessed in continuous operation?

With only 56 W at 37 °C, this incubator is extremely energy-efficient and keeps operating costs low, even in long-term operation.

What special features does apt.line technology offer?

It ensures fast and extremely homogeneous temperature distribution - temperature fluctuations within the sample series are reduced to a minimum.

Conclusion

The BD 400 offers an optimal combination of volume, temperature precision, energy efficiency and ease of use for demanding applications in research, development and quality control. Its DIN 12880 certification and particularly homogeneous temperature control thanks to apt.line technology make it the incubator of choice for laboratories and pharmaceutical companies that depend on maximum accuracy and reliability.