BIOTEC-FISCHER PHERO-DGGE vertical electrophoresis system in Electrophoresis Units

BIOTEC-FISCHER PHERO-DGGE vertical electrophoresis system

Denaturing Gradient Gel Electrophoresis (DGGE) is an important technique used in the search for mutations and DNA polymorphisms critical in genetic disorders and cancers, and to understand genetic diversity among species. The PHERO-DGGE is a flexible and customisable system that can perform several different mutation detection techniques. The PHERO-DGGE - a versatile single-unit solution for different single-base pair mutation detection methods. The newly designed PHERO-DGGE is a complete system for DNA mutation analysis. The new PHERO-DGGE is fully equipped with temperature control unit, stirrer, and gradient mixer and casting accessories to perform specific mutation analysis applications. A powerful microprocessor-controlled PID temperature control unit enables various mutation detection techniques to be undertaken between ambient temperature and 70°C. Accordingly, the new PHERO-DGGE can be used to screen single-base pair changes in the following applications:
Heteroduplex analysis (HA)
Parallel Denaturing Gradient Gel Electrophoresis (DGGE)
Constant Denaturing Gradient Gel Electrophoresis (CDGE)

The flexibility provided by the modular design of the PHERO-DGGE and its wide range of accessories enables laboratories to switch quickly and easily between different mutation detection techniques, thereby maximising throughput and screening efficiency. A maximum 96-sample throughput allows detection of as many mutations within a couple hours, alleviating many of the bottlenecks associated with screening for DNA mutations.


system includes:

• 1 x Notched glass plates (2 pcs.)
• 1 x Glass plate with spacer, 1.0 mm
• 1 x Comb, 24 slots, 1.0 mm
• 1 x Temperature control unit
• 1 x Gradient mixer & gel caster