Hettich Benchtop centrifuge ROTANTA 460

Hettich ROTANTA 460 bench-top centrifuge

The Hettich ROTANTA 460 bench-top centrifuge is a reliable laboratory component designed specifically for demanding centrifugation tasks in medical, biotechnological and research-oriented laboratories. With its powerful technology, flexible configuration and robust design, it is the preferred solution for the efficient separation of blood, biological substances and DNA. Its modular design, numerous expansion options and intelligent control system set it apart from comparable benchtop centrifuges and ensure maximum precision, safety and user-friendliness in daily routine and research operations.

Performance features and technical specifications

The ROTANTA 460 impresses with its wide range of applications, coupled with innovative features developed for both routine operation and complex methods in the life sciences and medical fields. Particularly noteworthy is the continuously adjustable cooling of the 460 R variant, which allows sensitive sample cycles at precisely controlled temperatures.

Important technical data at a glance:

• Maximum speed: 15,000 rpm
• Maximum RCF: 24,400 xg
• Maximum capacity: 4 x 750 ml (free-swing rotor) / 6 x 250 ml (angle rotor)
• Temperature range (cooled version): -20 °C to +40 °C, continuously adjustable
• Runtime control: 1 second to 99 hours, 59 minutes, 59 seconds; continuous and short runs also possible
• Dimensions: 456 x 554 x 706 mm (classic) or 456 x 770 x 706 mm (cooled)
• Weight: approx. 101 kg (classic), approx. 141 kg (cooled)

Additional features:

The benchtop centrifuge is compatible with a wide range of rotors - from high-capacity swing-out rotors for standard tubes and blood bags to special angle rotors for microtubes or microtitre plates. An innovative microprocessor control with an intuitive control panel facilitates the selection and fine adjustment of centrifugation programmes, while the display of error messages allows for a quick response to situations in everyday operation.

Sustainable durability and user protection:
The sophisticated air cooling system contributes twice to the longevity of the electronics and to the protection of temperature-sensitive samples. In addition, an automatic safety system - including lid lock and acoustic alarm - ensures maximum user protection.

• Medical device in accordance with 93/42/EEC
• Interference emission and immunity: EN / IEC 61326-1, Class B

These conformities are particularly essential for medical laboratories and practices with high quality standards.

Typical examples of use in everyday laboratory work

The versatile setting options and rotor variants make the ROTANTA 460 a universal solution for the following applications:

• Clinical laboratory diagnostics: Fractionation and separation of blood components (serum, plasma, erythrocytes) from samples with a volume of up to 4 x 750 ml; relevant for routine tests in hospitals, medical laboratories and blood banks.
• DNA and cell research: Isolation and purification of DNA, RNA or proteins using microtubes, e.g. for samples of tissue, cell lines or bacterial cultures; use of angle rotors for high RCF values with small volumes.
• Processing large sample volumes in biotechnology: Efficient sample preparation, for example for microtitre plate-based analyses or high-throughput diagnostics in the pharmaceutical sector.
• Specific separation tasks: Separation of emulsions (e.g. lipid analysis), suspensions or gas mixtures, where continuous temperature control is important for process reliability. Typical substances processed with this centrifuge include whole blood, serum, plasma, culture suspensions, extracted DNA, cell lysates, enzyme solutions and similar laboratory samples.

  FAQs

  Which rotors are compatible with the ROTANTA 460?

  • Compatible with swing-out rotors (e.g. 4 x 750 ml, max. RCF 5,063) and angle rotors (e.g. 30 x 1.5/2.0 ml, max. RCF 24,400; 6 x 250 ml, max. RCF 11,228).
  • Rotors for high-capacity microtitre plates (up to 12 plates per run) available.

  How is the temperature controlled for sensitive samples?

  • The cooled version allows precise temperature control from -20 °C to +40 °C, ideal for temperature-sensitive applications such as DNA analysis or protein preparation.

  What safety features does the device offer?

  • Fully automatic lid lock, acoustic alarm in case of errors, immediate display of error messages and quickly adaptable programmes for safe operation.

  Is the device certified for medical applications?

  • Yes, the centrifuge is approved as a medical device in accordance with 93/42/EEC and complies with EN / IEC 61326-1, Class B for electromagnetic compatibility.

  Conclusion

  The ROTANTA 460 benchtop centrifuge stands for efficiency, flexibility and uncompromising safety in the modern laboratory. With its robust construction, solution-oriented operating concept and versatile rotor options, it is an excellent investment for both everyday clinical use and specialised research projects. Its high RCF performance, variable temperature control and recognition by important standards and certifications make it the first choice for laboratories with the highest quality standards.