Hettich MIKRO 220 microlitre centrifuge
The Hettich MIKRO 220 microlitre centrifuge is a high-performance small laboratory centrifuge that has been specially developed for demanding applications in molecular biology, medical and biochemical laboratories. With its exceptional flexibility, precise control and a wide range of rotors, it is ideal for separating small sample volumes, as required in DNA/RNA analysis, clinical diagnostics or blood processing. Compared to similar models, this device stands out with its super sturdy design and long-lasting performance, advanced cooling, and user-friendly interface, making it the go-to solution for professional lab environments.
Performance features and technical highlights
With state-of-the-art microprocessor control, individually adjustable programmes and a comprehensive safety system, the MIKRO 220 meets the requirements for maximum precision and versatility in laboratory operations. The most important technical data and functions that maximise user value include:
- Maximum speed: 18,000 min-¹ (rpm)
- Maximum centrifugal force (RCF): 31,514 xg
- Vessel volume: 0.2 ml to 50 ml (depending on the rotor)
- Max. capacity: up to 60 x 1.5/2.0 ml in pot rotor, 48 x 1.5/2.0 ml or 6 x 50 ml (cooled) in angle rotor, 24 x 1.5/2.0 ml in free-swinging rotor
- Dimensions (H x W x D): 313 x 330 x 420 mm (Classic), 313 x 330 x 650 mm (cooled)
- Weight: approx. 21 kg (Classic), approx. 42 kg (cooled)
- Temperature range with cooling: continuously adjustable from -20 °C to +40 °C
- Runtime modes: 1 s to 99 min 59 s, continuous operation or short operation (pulse button)
In addition, all device variants are certified according to EN / IEC 61326-1, Class B and are IVD-compliant according to 98/79/EC. This ensures maximum electromagnetic compatibility and suitability for in vitro diagnostic processes as well as regulatory safety for use in the medical and diagnostic fields.
Special features:
The microlitre centrifuge is equipped with an acoustic warning system, automatic lid locking and immediate error message display. The maintenance-free, powerful air cooling in the Classic version and the infinitely variable temperature control (cooled version) protect sensitive samples from heat exposure and enable use for thermolabile substances.
The microprocessor with modern display allows complex centrifugation programmes to be stored and retrieved, supporting flexible adaptation to a wide range of method and protocol requirements. This is particularly useful for laboratories with changing routine work.
Certifications and standards
- EN / IEC 61326-1, Class B: Ensures electromagnetic compatibility in the laboratory environment.
- IVD compliance in accordance with Directive 98/79/EC: Confirmation of suitability for diagnostic samples in medical technology.
Specific examples of applications in laboratory practice
The MIKRO 220 is used in practical fields of work that require maximum separation performance, safety and flexibility. Typical applications are:
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DNA and RNA purification: Isolation and purification of nucleic acids from plasma lysates, cell lysates or biopsies for PCR, real-time PCR and sequencing analysis. Suitable for centrifugation of common kits and protocols.
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Clinical diagnostics: Pre-sorting and preparation of serum, plasma or blood samples (also in blood collection tubes up to 10 ml and standard tubes up to 50 ml in the refrigerated version) for immunological or clinical chemical analyses.
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Blood banks: Separation of different fractions such as erythrocytes, plasma and thrombocytes; also for thermolabile plasma fractions thanks to continuously adjustable cooling.
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Biochemical and pharmaceutical laboratories: Pelleting of macromolecules, microorganisms, cell fragments or protein suspensions. Areas of application include analyses of proteins, enzymes and virus preparations.
Typically used substances are:
- Plasmids, genomic DNA, RNA
- Blood components: plasma, serum, buffy coat
- Protein solutions, cell lysates, microorganisms
- Samples in diagnostic tubes (e.g. EDTA, heparin, citrate tubes)
FAQs
What rotor options are available and for which applications are they suitable?
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Angle rotor (24 x 1.5/2.0 ml): For standard DNA/RNA purifications, fast microcentrifugation steps, RCF up to 31,514 xg
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Angle rotor (48 x 1.5/2.0 ml, 2 rows): For high sample throughputs, e.g. screening in diagnostics or research, RCF 21,255 xg (outer), 18,845 xg (inner)
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Swing-out rotor (24 x 1.5/2.0 ml, 90°): For sensitive separations where the pellet is required to be centred at the bottom of the tube
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Angle rotor (6 x 50 ml, MIKRO 220 R only): For larger volumes, such as blood collection tubes or biochemical samples
How is temperature control ensured for sensitive samples?
The refrigerated version MIKRO 220 R features integrated continuous temperature control from -20 °C to +40 °C, allowing even temperature-sensitive substances to be centrifuged safely. The Classic version uses powerful air cooling to protect against overheating.
What safety features protect users and samples?
An automatic lid locking system, acoustic alarm in case of malfunctions, real-time display of error messages and protection against shock and vibration ensure maximum operational safety and an undisturbed working process.
How flexibly can the running time be adapted to different protocols?
Running times can be set individually from 1 second to 99 minutes and 59 seconds, or operated in continuous mode or via the pulse button for short runs. This offers maximum flexibility for a wide variety of sample preparations.
Conclusion
The Hettich MIKRO 220 microlitre centrifuge stands for high-quality equipment, precise handling and maximum safety, especially in molecular biology, clinical and diagnostic laboratories. Thanks to a large selection of compatible rotors, extensive safety features and exemplary cooling options, the centrifuge is recommended for a wide variety of separation processes - from routine processes to demanding research. Its robust construction, IVD compliance and user-friendly operation set standards in the compact high-performance centrifuge segment.
